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1.
Int. j. odontostomatol. (Print) ; 14(1): 67-72, mar. 2020. tab
Article in English | LILACS | ID: biblio-1056503

ABSTRACT

ABSTRACT: There has been little discussion about the quality of life of patients with maxillary defects. This article evaluates the issues related to the condition. We performed a cross-sectional study of patients with maxillary defects from referral centers in Brazil. To avoid subject burden, a questionnaire was developed, based on questions from seven instruments, which dealt with domains and conclusions that were similar to those from other studies. The predictor variable was the patients' score for each question. The outcome measure was the presence of the best-ranked items on the questionnaire as the impact factor. Six experts assessed these items and suggested which questions to include or exclude. Patients scored each item according to its occurrence and importance. Descriptive statistics and the items' rank according to the impact factor were computed to determine whether there is a comprehensive instrument available. Thirteen patients and six professionals were included in this study. The patients' age ranged from 24 to 72 years (mean (standard deviation, SD), 50.41 (14.46) years). We obtained a 60-item instrument from the selected questionnaires and subject interviews. Only 12 (37.5 %) out of the 32 best-rated items were verified by the existing instruments, two (6.25 %) were suggested by professionals and 18 (56.25 %) were conclusions from other studies. To the best of our knowledge, this is the first study to provide many features related to the quality of life in patients with maxillary defects.


RESUMEN: Existe escasa discusión en la literatura sobre la calidad de vida de los pacientes con defectos maxilares. Este artículo evalúa los problemas relacionados con esta condición. Realizamos un estudio transversal de pacientes con defectos maxilares de centros de referencia en Brasil. Se desarrolló un cuestionario basado en preguntas de siete instrumentos, que trataba sobre dominios y conclusiones similares a las de otros estudios. La variable de estimación fue la puntuación de los pacientes para cada pregunta. La medida de resultado fue la presencia de los elementos mejor clasificados en el cuestionario como factor de impacto. Seis expertos evaluaron estos ítems y sugirieron qué preguntas incluir o excluir. Los pacientes puntuaron cada ítem según su ocurrencia e importancia. Se calcularon las estadísticas descriptivas y la clasificación de los ítems según el factor de impacto, para determinar si existe un instrumento completo. Trece pacientes y seis profesionales fueron incluidos en este estudio. La edad de los pacientes osciló entre 24 y 72 años [media (desviación estándar), 50,41 (14,46) años]. Obtuvimos un instrumento de 60 ítems de los cuestionarios y entrevistas de temas seleccionados. Solo 12 (37,5 %) de los 32 ítems mejor calificados se verificaron de acuerdo a los instrumentos existentes, dos (6,25 %) fueron sugeridos por profesionales y 18 (56,25 %) fueron conclusiones de otros estudios. De acuerdo a nuestro conocimiento, este es el primer estudio que proporciona características relacionadas con la calidad de vida en pacientes con defectos maxilares.


Subject(s)
Humans , Adult , Middle Aged , Aged , Maxillary Diseases/pathology , Maxillary Diseases/epidemiology , Maxillary Neoplasms/pathology , Maxillofacial Prosthesis/classification , Maxillofacial Prosthesis/standards , Palatal Obturators , Palate/surgery , Quality of Life , Brazil , Maxillary Neoplasms/surgery , Cross-Sectional Studies , Surveys and Questionnaires , Ethics Committees , Data Analysis
2.
Int. j. odontostomatol. (Print) ; 13(4): 433-436, dic. 2019. graf
Article in English | LILACS | ID: biblio-1056480

ABSTRACT

ABSTRACT: Periapical cyst originates from an inflammatory reaction in the body that occurs due to a long-term endodontic aggression. It is more prevalent in caucasian male, during the third decade of life, in the anterior portion of the maxilla. They are commonly radiographic findings, due to their asymptomatic aspect. This study reports a Periapical Cyst in the portion corresponding to teeth 21, 22 and 23, which was treated by enucleation of the cyst, apicoectomy and retrograde root filling with Mineral trioxide aggregate (M.T.A) of teeth 21 and 22, filling of the cyst cavity with xenogeneic bone graft GenOx and a collagen membrane Gen-Derm. Observations after three months show good and rapid bone regeneration, periodontal and periapical health of the teeth involved.


RESUMEN: El quiste periapical se origina de una reacción inflamatoria que ocurre debido a una agresión endodóntica a largo plazo. Es más frecuente en el varón caucásico, durante la tercera década de la vida, en la porción anterior del maxilar. Son comúnmente hallazgos radiográficos, debido a su aspecto asintomático. En este estudio informamos acerca de un quiste periapical, en la porción correspondiente a los dientes 21, 22 y 23, que se trató mediante enucleación, apicectomía y relleno de raíz retrógrada con agregado de trióxido mineral (MTA) de los dientes 21 y 22, relleno de la cavidad del quiste con injerto óseo xenogénico Gen-Ox y una membrana de colágeno GenDerm. Las observaciones después de tres meses mostraron una buena y rápida regeneración ósea, con conservación de la salud periodontal y periapical de los dientes involucrados.


Subject(s)
Humans , Male , Middle Aged , Mandibular Diseases/pathology , Mandibular Diseases/diagnostic imaging , Maxillary Diseases/pathology , Maxillary Diseases/diagnostic imaging , Odontogenic Cysts/pathology , Odontogenic Cysts/diagnostic imaging , Bone Transplantation/methods , Radicular Cyst/diagnostic imaging , Bone Substitutes/therapeutic use , Oral Surgical Procedures
3.
Braz. oral res. (Online) ; 32: e64, 2018. tab, graf
Article in English | LILACS | ID: biblio-952162

ABSTRACT

Abstract This is a cross-sectional study that aimed to estimate maxillary sinus floor (MSF) pneumatization in single missing tooth of posterior maxilla, by using cone-beam computed tomography (CBCT). CBCT images were analyzed bilaterally and divided into 2 groups: edentulous site (EdS) - edentulous single region of upper second premolar, first or second molars; Tooth site (TS) - contralateral region homologous to the EdS region, with tooth present. Variables evaluated were: sinus height (SH), estimated sinus pneumatization (eSP: ∆ EdS - TS), healed ridge height (HR) and presence of localized sinus pneumatization (LSP) in molars teeth at TS. HR were categorized according to therapeutic option for posterior maxilla. 183 CBCT scans were included and it was observed that EdS presented a higher SH than the TS (p < 0.001) showing an eSP of 0.9 ± 2.93 mm. First molars presented the highest SH for both sides, although significant differences were detected when compared to second molars. First molars were mostly affected by LSP at TS (36 out of 43). Individuals with LSP at TS presented lower HR than the ones without LSP (p < 0.05). 54% of the cases presenting LSP obtained HR < 5 mm, which indicates sinus lift surgery. The present study showed that tooth loss in posterior maxilla favors sinus pneumatization and the identification of LSP at molar roots seems to indicate a greater necessity for sinus lift surgeries.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Aged , Aged, 80 and over , Young Adult , Maxillary Diseases/diagnostic imaging , Alveolar Bone Loss/diagnostic imaging , Tooth Loss/complications , Maxillary Sinus/diagnostic imaging , Palate/pathology , Palate/diagnostic imaging , Reference Values , Maxillary Diseases/etiology , Maxillary Diseases/pathology , Cross-Sectional Studies , Retrospective Studies , Analysis of Variance , Alveolar Bone Loss/etiology , Alveolar Bone Loss/pathology , Tooth Loss/diagnostic imaging , Statistics, Nonparametric , Cone-Beam Computed Tomography/methods , Alveolar Process/pathology , Alveolar Process/diagnostic imaging , Maxillary Sinus/growth & development , Maxillary Sinus/pathology , Middle Aged , Nasal Cavity/pathology , Nasal Cavity/diagnostic imaging
4.
J. appl. oral sci ; 26: e20170535, 2018. tab, graf
Article in English | LILACS, BBO | ID: biblio-954504

ABSTRACT

Abstract Giant Osteosclerotic Lesions (GOLs) are a group of rarely reported intraosseous lesions. Their precise diagnosis is important since they can be confused with malignant neoplasms. Objective This retrospective study aimed to record and analyze the clinical and radiographic Giant Osteosclerotic Lesions (GOLs) detected in the maxillomandibular area of patients attending to our institution. Materials and Methods: Informed consent from the patients was obtained and those cases of 2.5 cm or larger lesions with radiopaque or mixed (radiolucid-radiopaque) appearance located in the maxillofacial bones were selected. Assessed parameters were: age, gender, radiographic aspect, shape, borders, size, location and relations to roots. Lesions were classified as radicular, apical, interradicular, interradicular-apical, radicular-apical or located in a previous teeth extraction area. Additionally, several osseous and dental developmental alterations (DDAs) were assessed. Results Seventeen radiopacities in 14 patients were found and were located almost exclusively in mandible and were two types: idiopathic osteosclerosis and condensing osteitis. GOLs were more frequent in females, and in the anterior and premolar zones. 94.2% of GOLs were qualified as idiopathic osteosclerosis and one case was condensing osteitis. All studied cases showed different osseous and dental developmental alterations (DDAs). The most common were: Microdontia, hypodontia, pulp stones, macrodontia and variations in the mental foramina. Conclusions GOLs must be differentiated from other radiopaque benign and malignant tumors. Condensing osteitis, was considered an anomalous osseous response induced by a chronic low-grade inflammatory stimulus. For development of idiopathic osteosclerosis, two possible mechanisms could be related. The first is modification of the normal turnover with excessive osseous deposition. The second mechanism will prevent the normal bone resorption, arresting the osseous breakdown process.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Young Adult , Osteosclerosis/diagnostic imaging , Mandibular Diseases/diagnostic imaging , Maxillary Diseases/diagnostic imaging , Osteitis/pathology , Osteitis/diagnostic imaging , Osteosclerosis/pathology , Radiography, Panoramic , Mandibular Diseases/pathology , Maxillary Diseases/pathology , Retrospective Studies , Diagnosis, Differential , Middle Aged
5.
Article in English | IMSEAR | ID: sea-159298

ABSTRACT

The present article reports the case of a calcifying odontogenic cyst Type I variant in the maxilla of a 65-year-old woman. The lesion is unusual in that it has features of a cyst but also has many characteristics of solid neoplasm. It is classified into 2 types Type I-cystic variant and Type II-solid tumor variant. The calcifying odontogenic cyst may present some problems of differential diagnosis, both clinically and histopathologically. The histopathologic examination showed that structures characteristic of calcifying odontogenic cyst. The lesion was benign. After surgical removal of the cyst, the wound healed uneventfully, and the region was free of symptoms.


Subject(s)
Aged , Female , Humans , Maxilla , Maxillary Diseases/pathology , Odontogenic Cyst, Calcifying/diagnosis , Odontogenic Cyst, Calcifying/pathology , Odontogenic Cyst, Calcifying/surgery
6.
Odonto (Säo Bernardo do Campo) ; 20(40): 67-72, jul.-dez. 2012. tab, graf
Article in Portuguese | LILACS, BBO | ID: lil-790181

ABSTRACT

Introdução: O Tumor Odontogênico Ceratocístico (TOC) pode ser definido como um tumor intraósseo, benigno, de origem odontogênica. A incidência dessa lesão na mandibula é de 3 a 4 vezes maior que na maxila, com preferência pela região dos terceiros molares inferiores, no ângulo da madíbula, de onde se estende para o ramo ascentende. Em casos de lesões mais extensas, observa-se tumefação, drenagem ou dor associada, aumento de volume de tecidos moles e tecido ósseo, parestesia, mobilidade de dentes envolvidos pela lesão, bem como crescimento lento e deslocamento de peças dentárias. Objetivo e Metodologia: O objetivo deste trabalho foi realizar uma revisão da literatura e um levantamento de casos diagnosticados no Laboratóro de Patologia do Instituto de Ciências Biológicas da UPF a respeito do TOC. Resultados: No presente levantamento, foram encontrados 48 casos de TOC, com uma prevalencia do gênero feminino, na segunda e terceira década de vida. Um maior número de casos ocorreram na mandibula com preferencia pela região de terceiro molar inferior. Apresentavam em sua maioria lesões radiolúcidas uniloculares e o principal sinal clínico foi o de abaulamento. Conclusão: O que pode-se concluir através deste trabalho é que é fundamental para o sucesso do tratamento do Tumor Odontogênico Ceratocístico, o conhecimento por parte do Cirurgião Dentista de lesões tumorais de origem odontogênica , para que um correto e precoce diagnóstico seja executado, levando a melhor escolha do tratamento e, consequentemente um prognóstico favorável.


Introduction: The Keratocystic odontogenic tumor can be defined like an intraosseous tumor, benign, of odontogenic origin. The incidence of this lesion in the mandible and 3 to 4 times higher than in the maxilla, with a preference for the third molar region. In cases of more extensive lesions, there is swelling, drainage or pain associated, swelling of soft tissue and bone tissue, paresthesia, mobility of teeth involved by the injury, as well as slow growth and displacement of dental pieces. Objective and Methodology: The objective of this study was a literature review and a survey of cases diagnosed in the Pathology Lab of the Institute of Biological Sciences, UPF, about keratocystic odontogenic tumor. Result: In this survey, we found 48 cases of TOC, with a prevalence of females in second and third decade of life. A greater number of cases occurred in the jaw with a preference for the third molar region. Had mostly unilocular radiolucent lesions and was the main clinical sign of bulging. Conclusion: What can be concluded from this work is that it is essential for the successful treatment of odontogenic tumor keratocystic, knowledge by the Surgeon Dentist of odontogenic origin tumors, for a correct and early diagnosis is performed, taking the best choice of treatment and thus a favorable prognosis.


Subject(s)
Humans , Male , Female , Child , Adolescent , Young Adult , Middle Aged , Odontogenic Cysts/epidemiology , Odontogenic Cysts/pathology , Odontogenic Tumors/epidemiology , Odontogenic Tumors/pathology , Age Distribution , Brazil/epidemiology , Mandibular Diseases/epidemiology , Mandibular Diseases/pathology , Maxillary Diseases/epidemiology , Maxillary Diseases/pathology , Sex Distribution
7.
Odonto (Säo Bernardo do Campo) ; 20(40): 95-100, jul.-dez. 2012. ilus
Article in Portuguese | LILACS, BBO | ID: lil-790184

ABSTRACT

Objetivo: Os autores relatam um caso clínico de Displasia Cemento-Óssea Florida em mulher negra, 71 anos, desdentada, portadora de prótese total, com áreas hipercompressivas refletindo reação inflamatória no rebordo alveolar inferior. Descrição do caso: O tecido mole das áreas mucosas de rebordo se mostrava tumefacto difusamente, sugerindo fibromatoses localizadas. Radiograficamente, áreas radiopacas regulares e difusas eram observadas ao longo dos ossos maxilares. Biópsia em uma dessas áreas evidenciou, à microscopia óptica, quadro histopatológico compatível com displasia cementária, o que possibilitou o diagnóstico final de displasia cemento óssea florida, chamada também de cementoma gigantiforme, apesar de não representar uma verdadeira neoplasia. Conclusão: Os autores consideram, ainda, que não há relação com alterações sistêmicas de natureza hormonal ou metabólica e que na proposição do diagnóstico definitivo concorrem as características clínicas, radiográficas e histopatológicas.


Aim: The authors describe a clinical case of Florid Cemento-Osseous Dysplasia in black woman, 71 years old, edentous, bearer of total prosthesis, with areas hipercompressives reflecting inflammatory reaction in the inferior alveolar edge. Case description: The soft tissue of the mucous areas of edge was shown diffuse tumescent, suggesting located fibromatoses. Regular and diffuse radiopac radiographic areas were observed along the bones maxillaries. Biopsy in one of those areas evidenced, to the optical microscopy, histopathological images compatible with cementous dysplasia, what made possible the final diagnosis of Florid Cemento-Osseous Dysplasia, also called gigantiform cementoma, in spite of not representing a true neoplasm. Conclusion: The authors consider also that there is no relation with systemic hormonal or metabolic and the proposition that the definitive diagnosis is based in the clinical, radiographic and histopathologic features.


Subject(s)
Humans , Female , Aged , Maxillary Diseases/pathology , Bone Diseases, Developmental/pathology , Biopsy , Maxillary Diseases , Bone Diseases, Developmental , Mouth Mucosa/pathology , Alveolar Process/pathology
8.
Braz. oral res ; 26(4): 330-334, July-Aug. 2012. tab
Article in English | LILACS | ID: lil-640719

ABSTRACT

The purpose of this study was to determine the prevalence of odontogenic cysts and to identify their clinico-pathological features among patients by studying biopsy specimens obtained from the archives of the Department of Oral and Maxillofacial Pathology, College of Dental Sciences, Davangere, Karnataka, India, during the past 10 years. Data for the study were retrieved from the case records of patients fitting the histological classification of the World Health Organization (1992). Analyzed clinical variables included age, gender, anatomical location, and histological diagnosis. Of the 2275 biopsy reports analyzed, 194 cases (8.5%) were jaw cysts, including odontogenic (6.7%) and nonodontogenic cysts (0.25%). Odontogenic cysts included 69.3% radicular, 20.3% dentigerous, 5.2% keratinizing odontogenic, 3.3% residual, and 1.9% other cysts, such as lateral periodontal, botryoid odontogenic, and gingival cysts. The most frequent clinical manifestation was swelling, followed by a combination of pain and swelling. Age, gender, and location were related to the etiopathologic characteristics of the cyst type. A definitive diagnosis can be made on the basis of clinical, radiological, and histological findings, which makes a good interdepartmental relationship between the clinicians and pathologists essential. Knowledge of the biological and histological behavior of the odontogenic cysts is required for their early detection and treatment.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Middle Aged , Young Adult , Odontogenic Cysts/epidemiology , Odontogenic Cysts/pathology , Age Distribution , Age Factors , Biopsy , India/epidemiology , Mandibular Diseases/epidemiology , Mandibular Diseases/pathology , Maxillary Diseases/epidemiology , Maxillary Diseases/pathology , Prevalence , Sex Distribution
9.
Arch. oral res. (Impr.) ; 8(1): 81-85, jan.-abr. 2012. ilus
Article in English | LILACS, BBO | ID: lil-698605

ABSTRACT

Introduction: To report the treatment and follow-up (24 months) of a periodontal plastic surgery for excisionof a maxillary pyogenic granuloma. Case report: This case report describes a patient who presented alesion diagnosed as a pyogenic granuloma in the region of maxillary incisors and was submitted to surgicalexcision. The study emphasizes the clinical follow-up after the treatment of patients that present pyogenicgranuloma that should be based on surgical excision and histopathological confirmation of clinical diagnosiscombined with the treatment of the specific periodontal disease. Conclusion: Follow-up over two yearsof surgical procedures demonstrated the maintenance of a periodontal health.


Introdução: Relatar o tratamento e o acompanhamento clínico de 24 meses de uma cirurgia plástica periodontalpara excisão de um granuloma piogênico maxilar. Relato de caso: Este relato clínico descreve uma pacienteque apresentava uma lesão diagnosticada como granuloma piogênico na região de incisivos superiores e que foi submetida à excisão cirúrgica. O trabalho enfatiza o acompanhamento clínico após o tratamentode pacientes que apresentem granuloma piogênico, e que deve basear-se na excisão cirúrgica e na confirmaçãohistopatológica do diagnóstico clínico, combinado com o tratamento da doença periodontal específica.Conclusão: O acompanhamento clínico de dois anos dos procedimentos cirúrgicos indicou a manutenção dasaúde periodontal.


Subject(s)
Humans , Female , Pregnancy , Young Adult , Granuloma, Pyogenic/surgery , Periodontal Diseases/surgery , Follow-Up Studies , Granuloma, Pyogenic/pathology , Maxillary Diseases/pathology , Maxillary Diseases/surgery , Periodontal Diseases/pathology , Treatment Outcome
10.
Article in English | IMSEAR | ID: sea-140024

ABSTRACT

Glandular odontogenic cyst (GOC) is a recently recognized rare developmental odontogenic cyst having an aggressive behavior and accounting for 0.012% to 1.3% of all jaw cysts. GOC usually presents as a painless, slow-growing swelling that tends to affect the anterior part of the jaws. It chiefly occurs in the fourth and fifth decades of life and presents as an expansion of jaws with or without pain or paresthesia. Aggressive nature of the lesion has been reported, as supported by the fact that 25 to 55% of cases recur following curettage. So far only just over 113 cases of GOC have been reported in the literature. Here, we report a case of bilateral GOC in the posterior region of the maxilla, in a 29-year-old male patient, which is unique, being the first case of bilateral GOC to be reported in the literature.


Subject(s)
Adult , Connective Tissue/pathology , Diagnosis, Differential , Epithelium/pathology , Humans , Male , Maxillary Diseases/diagnosis , Maxillary Diseases/pathology , Mucins/analysis , Odontogenic Cysts/diagnosis , Odontogenic Cysts/pathology
11.
Article in English | IMSEAR | ID: sea-139970

ABSTRACT

The odontogenic keratocyst (OKC), first described by Phillipsen in 1956, has metamorphosized as a keratocystic odontogenic tumor (KCOT) as reported in WHO classification of head and neck tumors in 2005. KCOT is a benign intraosseous neoplasm of the jaw and its occurrence in maxilla is unusual and its appearance in maxillary antrum along with maxillary impacted third molar is very uncommon. This article reports a case of KCOT associated with impacted maxillary third molar in right maxillary antrum and describes its rare site of occurrence.


Subject(s)
Female , Humans , Maxillary Diseases/complications , Maxillary Diseases/pathology , Maxillary Diseases/surgery , Middle Aged , Molar, Third/pathology , Odontogenic Cysts/complications , Odontogenic Cysts/pathology , Odontogenic Cysts/surgery , Odontogenic Tumors/complications , Odontogenic Tumors/pathology , Odontogenic Tumors/surgery , Orthognathic Surgical Procedures/methods , Tooth, Impacted/complications , Tooth, Impacted/surgery , Treatment Outcome
12.
Article in English | IMSEAR | ID: sea-139968

ABSTRACT

Eruption cyst is a benign cyst associated with a primary or permanent tooth in its soft tissue phase after erupting through the bone. It is most prevalent in the Caucasian race. Intraoral examination of four patients revealed eruption cyst. Among these, in three patients it occurred in the maxillary arch and one had it in the mandibular arch. All were associated with permanent tooth. Surgical treatment was done in three cases and in one case the cyst disappeared gradually and tooth erupted in normal pattern. Four cases of eruption cyst from India are presented and literature on this condition is reviewed. It is clinically significant in that knowledge among general dentists is very essential regarding this developmental disturbance to reach the correct diagnosis and to provide proper treatment.


Subject(s)
Adolescent , Child , Humans , Male , Maxillary Diseases/pathology , Odontogenic Cysts/pathology , Odontogenic Cysts/surgery , Tooth Eruption , Treatment Outcome
13.
Braz. dent. j ; 22(3): 223-229, 2011. ilus, tab
Article in English | LILACS | ID: lil-595645

ABSTRACT

The aim of this study was to assess the immunohistochemical expression of syndecan-1 (CD138) and Ki-67 in radicular cysts (RC), dentigerous cysts (DC) and keratocystic odontogenic tumors (KOT). Thirty-five RC, 22 DC and 17 KOT were used in the study and immunohistochemical reactions using anti-syndecan-1 and anti-Ki-67 antibodies were performed by the streptavidin-biotin-peroxidase method. Fisher's exact test and Spearman's correlation coefficient were used for statistical analysis of data. Among the studied lesions, no differences in the syndecan-1 expression were observed, but the suprabasal expression of Ki-67 was significantly higher in KOT (p<0.0001), when compared with RC and DC. In RC, there was positive correlation between the expression (p=0.02) and intensity (p=0.0001) of syndecan-1 and between the intensity of syndecan-1 and Ki-67 expression (p=0.01). In the KOT, Ki-67 expression in the suprabasal layer correlated positively with the expression (p=0.01) and intensity (p=0.01) of syndecan-1. The expression of syndecan-1 does not seem to be a determinant factor of the distinct histopathological features and biological behavior of the studied lesions. Nevertheless, positive correlation between syndecan-1 and a cell proliferation marker was observed in RC and KOT.


O objetivo deste estudo foi avaliar a expressão imunoistoquímica de syndecan-1 (CD138) e Ki-67 em cistos radiculares (CR), cistos dentígeros (CD) e tumores odontogênicos queratocísticos (TOQ). Trinta e cinco CR, 22 CD e 17 TOQ foram utilizados no estudo e as reações imunoistoquímicas usando os anticorpos anti-syndecan-1 e anti-Ki-67 foram realizadas pelo método estreptavidina-biotina-peroxidase. Para análise estatística, o teste exato de Fisher e o coeficiente de correlação de Spearman foram utilizados. Entre as lesões estudadas, não foram observadas diferenças na expressão de syndecan-1, mas a expressão suprabasal de Ki-67 foi significativamente maior nos TOQ (p<0,0001), quando comparado aos CR e CD. No CR, havia correlação positiva entre a expressão (p=0,02) e intensidade (p=0,0001) de syndecan-1 e entre a intensidade de syndecan-1 e expressão de Ki-67 (p=0,01). No TOQ, a expressão de Ki-67 na camada suprabasal correlacionou positivamente com a expressão (p=0,01) e intensidade de expressão (p=0,01) de syndecan-1. A expressão de syndecan-1 não parece ser um fator determinante das características histopatológicas distintas e do comportamento biológico das lesões estudadas. Entretanto, correlação positiva entre syndecan-1 e um marcador de proliferação celular foi evidenciado em CR e TOQ.


Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Young Adult , /analysis , Odontogenic Cysts/pathology , Odontogenic Tumors/pathology , Syndecan-1/analysis , Antibodies , Cell Proliferation , Dentigerous Cyst/pathology , Epithelial Cells/pathology , Epithelium/pathology , Immunoenzyme Techniques , Immunohistochemistry , Mandibular Diseases/pathology , Mandibular Neoplasms/pathology , Maxillary Diseases/pathology , Retrospective Studies , Radicular Cyst/pathology
14.
Archives of Iranian Medicine. 2011; 14 (6): 416-418
in English | IMEMR | ID: emr-137337

ABSTRACT

The glandular odontogenic cyst is an uncommon developmental odontogenic cyst described as a distinct entity by Gardner et al. in 1988. The Glandular odontogenic cyst occurs more commonly in middle-aged people and has a predilection for the mandible. Only histopathological examinations allow for certain diagnosis of the cyst. The increased recurrence rate can be due to its multilocularity and incomplete removal of the lining following conservative treatment. This article presents a case of glandular odontogenic cyst in a 28-year-old male patient in the posterior region of the maxilla, which is quite rare


Subject(s)
Humans , Male , Maxillary Diseases/pathology , Odontogenic Cysts/diagnostic imaging , Odontogenic Cysts/surgery , Maxillary Diseases/diagnostic imaging , Maxillary Diseases/surgery
15.
Braz. dent. j ; 20(3): 237-342, 2009. tab
Article in English | LILACS | ID: lil-526417

ABSTRACT

The purpose of this study was to analyze the electromyographic (EMG) activity and the maximal molar bite force in women diagnosed with osteoporosis in the maxillary and mandibular regions, considering the habits and conditions that lead to development of generalized skeletal bone loss, including on face bones, can disturb the functional harmony of the stomatognathic system. Twenty-seven women with mandibular and maxillary osteoporosis and 27 healthy controls volunteered to participate in the study. A 5-channel electromyographer was used. Muscle activity was evaluated by means of EMG recordings of the masticatory musculature (masseter and temporalis muscles, bilaterally) during the following clinical conditions: rest (5 s); right and left lateral excursions (5 s); protrusion (5 s); maximal dental clenching on Parafilm™ (4 s) and maximal voluntary contraction (4 s). This latter clinical condition was used as the normalization factor of the sample data. It was observed that individuals with osteoporosis presented greater EMG activity when maintaining mandible posture conditions and less activity during dental clenching and when obtaining maximal molar bite force. It may be concluded that facial osteoporosis can interfere on the patterns of masticatory muscle activation and maximal bite force of the stomatognathic system.


Este estudo teve como objetivo analisar a atividade eletromiográfica e a força de mordida molar máxima de indivíduos diagnosticados com osteoporose na região maxilar e mandibular, visto que os hábitos e condições que provocam o desenvolvimento de uma perda óssea generalizada no esqueleto, inclusive no esqueleto facial, podem causar distúrbios na harmonia funcional do sistema mastigatório. Vinte e sete indivíduos portadores de osteoporose na mandíbula e maxila e 27 voluntários sem a doença participaram deste estudo. Um eletromiógrafo de 5 canais foi utilizado. A avaliação da atividade muscular foi realizada por meio de registros eletromiográficos da musculatura mastigatória (músculos masseter e temporal, bilateralmente) durante as seguintes condições clínicas: Repouso (5 s); Lateralidades direita e esquerda (5 s); Protrusão (5 s); Apertamento dental máximo com parafilme (4 s) e a contração voluntária máxima (4 s), sendo que esta condição clínica foi utilizada como fator de normalização dos dados da amostra. Verificou-se que os indivíduos com osteoporose apresentaram maior atividade eletromiográfica durante a manutenção das condições posturais da mandíbula e menor atividade durante o apertamento dental e na obtenção da força de mordida molar máxima. Conclui-se que a osteoporose na região dos ossos da face pode interferir nos padrões de ativação da musculatura mastigatória e na força de mordida máxima do sistema estomatognático.


Subject(s)
Aged , Female , Humans , Middle Aged , Bite Force , Mandibular Diseases/physiopathology , Masticatory Muscles/physiopathology , Maxillary Diseases/physiopathology , Osteoporosis/complications , Case-Control Studies , Cohort Studies , Dental Occlusion , Electromyography , Functional Laterality , Matched-Pair Analysis , Mandibular Diseases/complications , Mandibular Diseases/pathology , Maxillary Diseases/complications , Maxillary Diseases/pathology , Muscle Contraction/physiology , Osteoporosis/pathology , Osteoporosis/physiopathology , Reference Values
16.
Article in English | IMSEAR | ID: sea-51881

ABSTRACT

Central giant cell granuloma (CGCG) formerly called giant cell reparative granuloma is a non-neoplastic proliferative lesion of unknown etiology. It occurs most commonly in the mandible. The case reported here resembled a wide variety of conditions that led to a misdiagnosis both on clinical and radiographic examination but was histopathologically diagnosed as CGCG. We describe a case of central giant cell granuloma arising from the anterior maxilla to highlight to the general dental practitioner the importance of histopathology in the diagnosis of this enigmatic lesion.


Subject(s)
Adult , Diagnosis, Differential , Granuloma, Giant Cell/pathology , Humans , Male , Maxillary Diseases/pathology
18.
Braz. oral res ; 21(3): 216-221, 2007. ilus, graf, tab
Article in English | LILACS | ID: lil-458593

ABSTRACT

The purpose of this study was to compare histologic and morphometric procedures of bone height measurement. Microscopic measurements are the most frequent methods in periodontal studies with animals, but have limited capacity to identify bone levels associated with both healthy tissues and periodontal disease. Ligatures were placed in the maxillary left second molars of 10 male 60-day-old Wistar rats for 30 days. Left and right maxillary sides of 5 rats were processed for histologic analysis (H), sectioned buccolingually, and stained with HE. The maxillae of the other 5 rats were defleshed and used for morphometric analysis (M). Histometric measurements from the cementoenamel junction to the bone crest were performed. Standardized photographs were used for morphometric analysis. The t test was used for dependent or independent samples (alpha = 0.05 percent). Distances from cementoenamel junction to bone crest were 0.95 ± 0.25 and 1.07 ± 0.30 mm for H and M, respectively. Buccal measurements were 0.92 ± 0.16 and 1.08 ± 0.35 mm for H and M. The values obtained using H and M for areas without ligatures were 0.44 ± 0.15 and 0.47 ± 0.11 mm for lingual measurements and 0.23 ± 0.08 and 0.41 ± 0.10 mm for buccal measurements. No significant differences were found between the two methods in the detection of bone height associated with the placement of ligatures in rats.


O objetivo deste estudo foi comparar procedimentos de medida da altura óssea histológica e morfométrica. O método mais freqüente de mensuração da altura óssea em estudos em animais são as medidas microscópicas. No entanto, tem limitada capacidade de identificar os níveis ósseos associados com os tecidos saudáveis e doença periodontal. Foram colocadas ligaduras no segundo molar superior esquerdo de 10 ratos machos Wistar com 60 dias de vida durante um período de 30 dias. Hemimaxilas direitas e esquerdas de 5 ratos foram processadas para a análise histológica (H), cortadas no sentido vestíbulo-lingual e coradas com HE. Hemimaxilas dos outros 5 ratos tiveram toda a matéria orgânica removida para análise morfométrica (M). Medidas histométricas da junção cemento-esmalte (JCE) à crista óssea alveolar foram realizadas. Fotografias padronizadas foram utilizadas na análise morfométrica. O teste t foi utilizado para amostras dependentes e independentes (alfa = 0,05 por cento). As distâncias entre a JCE e a crista óssea na face palatina foram de 0,95 ± 0,25 e 1,07 ± 0,30 mm para H e M, respectivamente. As medidas vestibulares foram 0,92 ± 0,16 e 1,08 ± 0,35 mm para H e M. Os valores obtidos usando H e M para áreas sem ligadura foram 0,44 ± 0,15 e 0,47 ± 0,11 mm por lingual e 0,23 ± 0,08 e 0,41 ± 0,10 mm por vestibular, respectivamente. Não houve diferenças estatisticamente significativas entre os dois métodos na detecção da altura óssea associada à colocação de ligaduras em ratos.


Subject(s)
Animals , Male , Rats , Alveolar Bone Loss/pathology , Periodontitis/pathology , Alveolar Bone Loss/etiology , Bone Resorption/pathology , Disease Models, Animal , Germ-Free Life , Ligation , Maxillary Diseases/etiology , Maxillary Diseases/pathology , Periodontitis/chemically induced , Rats, Wistar
19.
Indian J Pathol Microbiol ; 2006 Jul; 49(3): 445-7
Article in English | IMSEAR | ID: sea-73326

ABSTRACT

Nonodontogenic cysts have been identified at various locations in oral cavity. These occur primarily in relation to fusion of maxillary process either with its counterpart or different portions of nasal part of frontonasal process. Usually solitary, these primarily affect maxilla alone; can rarely be seen in ramus of mandible. We present a case of multiple non-odontogenic cysts involving both maxilla and mandible.


Subject(s)
Adult , Humans , Male , Mandible/pathology , Mandibular Diseases/pathology , Maxilla/pathology , Maxillary Diseases/pathology , Nonodontogenic Cysts/pathology , Tomography, X-Ray Computed
20.
Rev. bras. odontol ; 63(1/2): 120-122, 2006. graf
Article in Portuguese | LILACS, BBO | ID: lil-438473

ABSTRACT

Dentre os pacientes portadores de infecções odontogênicas internados no HGJAF (1999-2004), foram analisados dados tais como: sexo, idade, procedência, diagnóstico, tratamento, uso de antibiótico, período de internação e evolução. Houve predomínio de pacientes do sexo masculino (57,32%) entre 21 e 30 anos (32,92%, procedentes do interior (54,88%). Abscesso foi a infecção mais frequente (51,22%). O tratamento medicamentoso predominou (62,20%), com uso de antibióticos (100%), mais frequentemente a penicilina (39,71%). Cinco dias foi o período médio de internação, evoluindo para alta hospitalar (98,78%). O tratamento terapêutico-cirúrgico, apesar de não ter sido o mais frequente, é o de escolha, por obter resultados satisfatórios em menor período


Subject(s)
Humans , Male , Female , Abscess/therapy , Mandibular Diseases/pathology , Mandibular Diseases/therapy , Maxillary Diseases/pathology , Maxillary Diseases/therapy , Bacterial Infections/therapy , Age and Sex Distribution , Retrospective Studies
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